陈庆副教授

发布者:张欧扬发布时间:2016-03-14浏览次数:11020

陈庆博士、副教授  



个人简历:

2005年就读于中国药科大学中药化学专业,2007年提前攻读中国药科大学中药学专业博士学位,2010年毕业获理学博士学位。20109月获聘就职于厦门大学。主要从事药物分析中的分子印迹技术研究,电化学在基因检测中的研究及中药活性成分的产品开发与质量控制。

 

教育背景:

2005-2007中国药科大学中药化学专业

2007-2010中国药科大学中药学专业 获博士学位

 

主要研究方向:

课题组一直致力于药品质量控制和中药有效成分的研究与开发。 以分子印迹和电化学技术为核心,对复杂底物(如血液样本、中药提取物)中的基因、蛋白质等生物靶标和活性指标进行了准确高效的快速检测,优化痕量有效成分的分离分析工艺。分析方法先进,成果已发表在高水平论文中。 

1. 分子印迹技术在药物分析中的应用。

2. 电化学在复杂基体中活性组分或靶点分析中的应用。 

3. 中药活性成分产品开发与质量评价。

 

代表性论文

(1)    Jingbo Zhang(†), Quancheng Chen(†), Xuemin Gao, Qian Lin, Ziqin Suo, Di Wu, Xijie Wu*, Qing Chen*.A Label-free and Antibody-free Molecularly Imprinted Polymer-based Impedimetric Sensor for NSCLC cells Derived Exosomes Detection. Biosensors, 2023, 13(6), 647 https://doi.org/10.3390/bios13060647

(2)    Huayu Yang (†), Hua Song (†), Ziqin Suo, Funan Li, Quanyi Jin, Xuan Zhu*, Qing Chen *. A molecularly imprinted electrochemical sensor based on surface imprinted polymerization and boric acid affinity for selective and sensitive detection of P-glycoproteins.Analytica Chimica Acta, 2022, 1207: 339797

(3)    Qing Chen (†) *, Xinmei Liu (†), Huayu Yang, Shuyi Zhang, Hua Song, Xuan Zhu *. Preparation and evaluation of magnetic graphene oxide molecularly imprinted polymers (MIPs-GO-Fe3O4@SiO2) for the analysis and separation of tripterine. Reactive and Functional Polymers, 2021,169: 105055

(4)    Xiaoxue Wu(†), Xuemin Gao(†), Xinmei Liu, Shuyi Zhang, Huayu Yang, Xuan Zhu, Hua Song, Funan Li and Qing Chen*. Quality Control of Psoralea corylifolia L. Based on High-Speed Countercurrent Chromatographic Fingerprinting. Molecules, 2020, 25(2): 279-292

(5)    Xiaoxue Wu(†) , Xuemin Gao(†), Xuan Zhu, Shuyi Zhang, Xinmei Liu, Huayu Yang, Hua Song and Qing Chen*. Fingerprint Analysis of Cnidium monnieri (L.) Cusson by High-Speed Counter-Current Chromatography. Molecules, 2019, 24(24): 4496-4510

(6)    Yilin Chen(†)Qing Chen(†) Qixin Zhu, Jinxue Liu, Yang Li, Xuemin Gao, Dengyue Chen* and Xuan Zhu*. Small Molecular Theranostic Assemblies Functionalized by Doxorubicin−Hyaluronic Acid−Methotrexate Prodrug for Multiple Tumor Targeting and Imaging-Guided Combined Chemo-Photothermal Therapy. Molecular Pharmaceutics2019, 16, 2470−2480

(7)    Qing Chen (†), Xiaoxue Wu (†), Xuemin Gao, Hua Song (*) and Xuan Zhu (*), Development and validation of an Ultra-Performance Liquid Chromatography method for the determination of Wedelolactone in rat plasma and its application in a pharmacokinetic study, Molecules, 2019, 24(4): 762.

(8)    Yu Zhou, Wushuang Yang, Zhiqun Li, Doudou Luo, Weijie Li, Yali Zhang, Xuan Wang, Meijuan Fang, Qing Chen(*), Xin Jin*, Moringa oleifera stem extract protect skin keratinocytes against oxidative stress injury by enhancement of antioxidant defense systems and activation of PPARα, Biomedicine & Pharmacotherapy2018, 107: 44-53

(9)    Jing Wang (†), Hua Song (†), Xiaoxue Wu, Shuyi Zhang, Xuemin Gao, Funan Li, Xuan Zhu (*) and Qing Chen (*), Steroidal saponins from Vernonia amygdalina Del. and their biological activity, Molecules. 2018, 23(3): 579-589.

(10)  Dan Zhao (†), Qing Chen(†), Hua Song*, Shuting Luo, Pingyun Ge, Yingjun Wang, Jinyuan Ma, Zhi Li, Xuemin Gao, Xuemei Zhao, Xiayiding Subinuer, Huayu Yang, Xiaojuan Jiang, Yanxin Chen, Xuan Zhu, Theranostic micelles combined with multiple strategies to effectively overcome multidrug resistance.Nanomedicine, 2018, 13(13): 1517-1533

(11)  Yuxin Guo, Yang Zhang, Jinyuan Ma, Qi Li, Yang Li, Xinyi, Zhou, Dan Zhao, Hua Song, Qing Chen(*), Xuan Zhu*, Light/magnetic hyperthermia triggered drug released from multi-functional thermo-sensitive magnetoliposomes for precise cancer synergetic theranostics. Journal of Controlled Release, 2018,272: 145-158

(12) Guihua Liu, Jinyuan Ma, Yang Li, Qi Li, Chunhua Tan, Hua Song, Shuhui Cai, Dengyue Chen, Zhengqing Hou, Qing Chen(*), Xuan Zhu*, Core-interlayer-shell Fe3O4@mSiO2@lipid-PEG-methotrexate nanoparticle for multimodal imaging and multistage targeted chemo-photodynamic therapy. International Journal of Pharmaceutics, 2017, 521(1-2):19–32

(13) Qing Chen, Lichao Diao, Hua Song, Xuan Zhu*, Vitis amurensis Rupr: A review of chemistry and pharmacology, Phytomedicine, 2018,49111-122

(14) Hua SongJianhong LinXuan ZhuQing Chen (*)Developments in high-speed countercurrent chromatography and its applications in the separation of terpenoids and saponinsJournal of Separation Science, 2016, 39(8) : 1574-1591

(15)Jing Lin, Hongjie Wu, Yingjun Wang, Jianhong Lin, Qing Chen (*),  Zhu Xuan(*) , Preparation and ocular pharmacokinetics of hyaluronan acid-modified mucoadhesive liposomes, Drug Delivery, 2016, 23(4) : 1144-1151 

(16)  Chen QingLin JianhongZhao DanZhu Xuan(*) Isolation and Stucture Elucidation of Diterpenes from Wedelia prostrata and Their Cytotoxicity ActivitiesChemical Research in Chinese Universities201632(5): 792-796

(17) Qing Chen, JianguangLuo, Lingyi Kong*. New triterpenoid saponins from the roots of Gypsophila perfoliata Linn. Carbohydrate Research, 2011, 346(14): 2206-2212

(18)  Qing Chen, Jianguang Luo and Lingyi Kong*. Triterpenoid Saponins from Gypsophila altissima L. Chemical & Pharmaceutical Bulletin, 2010, 58(3): 412-414

(19) Qing Chen, Shun Yao, Xuefeng Huang, JianguangLuo, Junsong Wang, Lingyi Kong*.Supercritical fluid extraction of Coriandrum sativum and subsequent separation of isocoumarins by high-speed counter-current chromatography. Food Chemistry, 2009, 117 (3): 504-508

(20)  林友文,陈庆,罗红斌,N-2-磺酸基苯甲基)壳聚糖的合成、表征及其水凝胶的pH敏感性,高等学校化学学报,2007, 28(1): 183-187

联系方式:

地址:福建省厦门市翔安区翔安南路厦门大学药学院251

邮编:361102

Email: chenqing@xmu.edu.cn