程亚彬博士、助理教授
个人简介:
程亚彬博士的研究主要涉及肿瘤发病机制、蛋白质修饰与蛋白质稳态、利用组织芯片技术的诊断及预后标记物研发、新型抗肿瘤药物靶点及药物研发等。先后主持或参与国家、省级科研基金项目7项,研究成果已发表研究论文30余篇,包括Molecular Cell、Journal of Investigative Dermatology、British Journal of Cancer、Oncogene等国际主流医学生物学期刊,2018年入选福建省B类高层次海外引进人才。
教育及工作经历:
2000-2004 中国海洋大学本科(药学)
2004-2007 中国海洋大学硕士(药理学)
2008-2014 加拿大英属哥伦比亚大学博士(实验医学)
2014-2015 加拿大英属哥伦比亚大学博士后(皮肤病学系)
2015-至今厦门大学药学院助理教授
代表性论文(更新至2021年3月):
1. Yingying Lin#, Fajin Li#, Linlu Huang, Christine Polte, Haoran Duan, Jianhuo Fang, Li Sun, Xudong Xing, Guiyou Tian, Yabin Cheng*, Zoya Ignatova, Xuerui Yang*, Dieter A. Wolf*. eIF3 Associates with 80S ribosomes to promote translation elongation, mitochondrial homeostasis, and muscle health. Mol Cell. 2020 Aug 20;79(4):575-587.e7. (共同通讯作者, IF:15.584, 一区)
2. Dieter A. Wolf*, Yingying Lin, Haoran Duan, Yabin Cheng. eIF-three to tango: emerging function of translation initiation factor eIF3 in protein synthesis and disease. J Mol Cell Biol. 2020 Jul 3;12(6):403-409. (IF:4.000, 二区)
3. Xin Chen#, Xiaosong Liu#, Bin Deng, Magdalena Martinka, Youwen Zhou, Xiaopeng Lan*, YabinCheng*. Cytoplasmic Pin1 expression is increased in human cutaneous melanoma and predicts poor prognosis. Sci Rep. 2018 15;8(1):16867. (共同通讯作者, IF:3.998, 三区)
4. Jiaying Zhou#, Yabin Cheng#*, Liren Tang, Magdalena Martinka, Sunil Kalia*, Up-regulation of SERPINA3 correlates with high mortality of melanoma patients and increase migration and invasion of cancer cells, Oncotarget, 2017, 8(12):18712-18725. (共同第一作者, IF:5.168, 二区)
5. Joshua Jiawei Zhou, Yuanshen Huang, Xue Zhang, Yabin Cheng*, Liren Tang*, Xiaodong Ma*, Eyes absent gene (EYA1) is a pathogenic driver and a therapeutic target for melanoma, Oncotarget, 2017, 8(62):105081-105092. (共同通讯作者, IF:5.168, 二区)
6. Yabin Cheng, Jing Lu, Guangdi Chen, Gholamreza Safaee Ardekani, Anand Rotte, Magdalena Martinka, Xuezhu Xu, Kevin McElwee, Guohong Zhang*, Youwen Zhou*, Stage-specific prognostic biomarkers in melanoma, Oncotarget, 2015, 6(6): 4180-4189. (共同第一作者, IF:5.168, 二区)
7. Jing Lu#*, Yabin Cheng#, Guohong Zhang, Yun Tang, Ziming Dong, Kevin J. McElwee* and Gang Li, Increased expression of Neuropilin 1 in melanoma progression and its prognostic significance in melanoma patients, Mol Med Rep, 2015, 12(2):2668-76. (共同第一作者, IF:2.100, 四区)
8. Yabin Cheng, Guangdi Chen, Magdalena Martinka, Vincent Ho, Gang Li*, Prognostic significance of Fbw7 in human melanoma and its role in cell migration, Journal of Investigative Dermatology, 2013, 133(7): 1794-1802. (第一作者, IF:7.143, 一区)
9. Yabin Cheng, Gang Li*, Role of the ubiquitin ligase Fbw7 in cancer progression, Cancer Metastasis Rev, 2012, 31(1): 75-87. (第一作者, IF:6.400, 二区)
10. Yabin Cheng, Jun Li, Magdalena Martinka, Gang Li*. The expression of NAD(P)H:quinoneoxidoreductase 1 is increased along with NF-κB p105/ p50 in human cutaneous melanomas, Oncology Reports, 2010, 23 (4): 973-979. (第一作者, IF:3.417, 三区)
参与书籍编写
1. 流行病学,第3卷/沈红兵主编,第3版,人民卫生出版社,2014年9月,ISBN:978-7-117-18589-9。编写第二十九章皮肤癌,第385-397页。
2. Genome Stability, From Virus to Human Application, Igor Kovalchuk/Olga Kovalchuk主编,Elsevier出版社,2016年,ISBN:978-0-12-803309-8,编写第27章,Cancer and Genomic Instability, 463-486。