吴云龙教授

发布者:张欧扬发布时间:2016-03-14浏览次数:16788


吴云龙博士,教授



个人简介:

    吴云龙,2005年取得中国科学技术大学材料化学专业理学学士学位,2011年获新加坡国立大学生物工程博士学位。2010-2012年在南洋理工大学材料科学与工程学院从事博士后工作。2012年应聘为厦门大学药学院助理教授,2014年聘为厦门大学药学院副教授,2019年聘为厦门大学药学院教授。主要研究方向:超分子自组装、基于环糊精的药物或基因载体设计、细胞牵引力显微镜。主要研究成果包括利用环糊精的分子识别操控其自组装为有序超分子结构,并探索超分子结构作为药物载体的优势。同时还对于细胞牵引力显微镜的开发用于观测细胞物理性能的实时动态变化过程有着浓厚的兴趣。近年,主持了国家自然科学基金面上基金项目(201981971724201781773661)、福建省高校杰出青年科研人才培育计划项目(2018年)、国家自然科学基金青年基金项目(21303145)、福建省自然科学基金面上基金项目(2014J01063)、中央专项基本科研项目(201312103720720170066)、院长基金等多项科研项目。

 

教育及工作经历:

2001.09-2005.07  中国科学技术大学,  材料化学学士;

2005.08-2011.06  新加坡国立大学,生物工程博士;

2009.09-2010.03  新加坡国立大学,生物工程系研究工程师;

2011.08          德国海德堡大学,合作研究者;

2010.05-2012.05  新加坡南洋理工大学,材料科学与工程学院博士后;

2012.06-2014.07  厦门大学药学院,助理教授;

2014.08-2019.07  厦门大学药学院,副教授;

2019.08-至今:  厦门大学药学院,教授。

 

发表论文目录*通讯作者)

2021

1.         Liu, M.; Wu, C.; Ke, L.; Li, Z.; Wu, Y.-L.*“Emerging Biomaterials-Based Strategies for Inhibiting Vasculature Function in Cancer Therapy.”Small Methods, 2021, DOI: 10.1002/smtd.202100347. (SCI impact factor: 12.130)

2.         Li, Z.; Cheng, H.; Ke, L.; Liu, M.; Wang, C.-G.; Loh, X.; Li, Z.*; Wu, Y.-L.* “Recent Advances in New Copolymer Hydrogel-Formed Contact Lenses for Ophthalmic Drug Delivery.” ChemNanoMat, 2021, DOI: 10.1002/cnma.202100008. (SCI impact factor: 3.384)

3.         Han, Y.; Xu, C.; Shi, H.; Yu, F.; Zhong, Y.; Liu, Z.; Loh, X. J.; Wu, Y.-L.*; Li, Z.*; Li, C.* “Engineered Bio-adhesive Polyhedral Oligomeric Silsesquioxane Hybrid Nanoformulation of Amphotericin B for Prolonged Therapy of Fungal Keratitis.Chemical Engineering Journal, 2021, 421: 129734. (SCI impact factor: 10.652)

4.         Wu, Y.-L.*; Li, Z.* “Recent Advances on Noninvasive Ocular Therapeutic Delivery Strategy Based on Polymeric Formulations.” Therapeutic Delivery, 2021, DOI: 10.4155/tde-2021-0030.

5.         Jiang, X.; Li, Z.; Young, D. J.; Liu, M.; Wu, C.*; Wu, Y.-L.*; Loh, X.* “Towards the Prevention of Coronavirus Infection: What Role Can Polymers Play?” Materials Today Advances, 2021, 10: 100140.

6.         Fan, X.; Luo, Z.; Ye, E.*; You, M.; Liu, M.; Yun, Y.; Loh, X. J.; Wu, Y.-L.*; Li, Z.* “AuNPs Decorated PLA Stereocomplex Micelles for Synergetic Photothermal and Chemotherapy.Macromolecular Bioscience, 2021, DOI: 10.1002/mabi.202100062. (SCI impact factor: 3.416)

7.         Ke, L.; Li, Z.; Fan, X.; Loh, X. J.; Cheng, H.*; Wu, Y.-L.*; Li, Z.* Cyclodextrin-Based Hybrid Polymeric Complex to Overcome Dual Drug Resistance Mechanisms for Cancer Therapy.Polymers, 2021, 13(8): 1254. (SCI impact factor: 3.426)

8.         Chen, X.#; Wu, Y.-L.#; Chen, C.#; Gu, Y.; Zhu, C. Wang S.; Chen, J.; Zhang, L.; Lv, L.; Zhang, G.; Yuan, Y.; Chai, Y.*; Zhu, M.*; Wu, C.* Identifying Potential Anti-COVID-19 Pharmacological Components of Traditional Chinese Medicine Lianhuaqingwen Capsule Based on Human Exposure and ACE2 Biochromatography Screening.Acta Pharmaceutica Sinica B, 2021, 11(1): 222-236. (SCI impact factor: 7.097)

9.         Loh, X. J.*; Young, D. J.; Guo, H.; Tang, L.; Wu, Y.-L.; Zhang, G.; Tang, C.; Ruan, H.* ²Pearl Powder - An Emerging Material for Biomedical Applications: A Review.²Materials, 2021, 14: 2797. (SCI impact factor: 3.267)

2020

10.     Luo, Z.; Jiang, L.; Xu, C.; Kai, D.; Fan, X.; You, M.; Hui, C.M.; Wu, C.*; Wu, Y.-L.*; Li, Z.* Engineered Janus Amphipathic Polymeric Fiber Films with Unidirectional Drainage and Anti-Adhesion Abilities to Accelerate Wound Healing.Chemical Engineering Journal, 2020, DOI: 10.1016/j.cej.2020.127725. (SCI impact factor: 10.652)

11.     Hu, B.; Berkey, C.; Feliciano, T.; Chen, X.; Li, Z.; Chen, C.; Amini, S.; Nai, M.H.; Lei, Q.-L.; Ni, R.; Wang, J.; Leow, W.R.; Pan, S.; Li, Y.-Q.; Cai, P.; Miserez, A.; Li, S.; Lim, C.T.*; Wu, Y.-L.*; Odom, T.W.*; Dauskardt, R.H.*; Chen, X.* Thermal-Disrupting Interface Mitigates Intercellular Cohesion Loss for Accurate Topical Antibacterial Therapy.Advanced Materials, 2020, 32(12): 1907030. (SCI impact factor: 25.809)

12.     Ke, L.; Cai, P.; Wu, Y.-L.*; Chen, X.* “Polymeric Nonviral Gene Delivery Systems for Cancer Immunotherapy.” Advanced Therapeutics, 2020, 3(6): 1900213.

13.     Luo, Z.; Xue, K.; Zhang, X.; Lim, J. Y. C.; Lai, X.; Young, D. J.; Zhang, Z.-X.*; Wu, Y.-L.*; Loh, X. J.* Thermogelling Chitosan-Based Polymers for the Treatment of Oral Mucosa Ulcers.Biomaterials Science, 2020, 8(5): 1364-1379. (SCI impact factor: 5.251)

14.     Liu, Y.; Xu, C.; Fan, X.; Loh, X. J.; Wu, Y.-L.*; Li, Z.* “Preparation of Mixed Micelles Carrying Folates and Stable Radicals Through PLA Stereocomplexation for Drug Delivery.” Materials Science and Engineering: C, 2020, 108: 110464. (SCI impact factor: 4.959)

2019

15.     Luo, Z.; Jiang, L.; Yang, S.; Li, Z.*; Soh, W. M. W.; Zheng, L.*; Loh, X. J.*; Wu, Y.-L.*Light-Induced Redox-Responsive Smart Drug Delivery System by Using Selenium-Containing Polymer@MOF Shell/Core Nanocomposite.Advanced Healthcare Materials, 2019, 8(15): 1900406. (SCI impact factor: 6.270)

16.     Wu Y.-L.*; Li, Z* The Perspectives of Using Unimolecular Micelles in Nanodrug Formulation.Therapeutic Delivery, 2019, 10(6): 333-335.

17.     Liu, X.; Li, Z.; Loh, X.; Chen, K.; Li, Z.; Wu Y.-L.*Targeted and Sustained Co-Release of Chemotherapeutics and Gene by Injectable Supramolecular Hydrogel for Drug-Resistant Cancer Therapy.Macromolecular Rapid Communications, 2019, 40(5): 1800117. (SCI impact factor: 4.078)

18.     Cheng, H.; Fan, X.; Wu, C.; Wang, X.; Wang, L.-J.; Loh, X.-J.*; Li, Z.*; Wu Y.-L.*Cyclodextrin-Based Star-Like Amphiphilic Cationic Polymer as a Potential Pharmaceutical Carrier in Macrophages.Macromolecular Rapid Communications, 2019, 40(5): 1800207. (SCI impact factor: 4.078)

19.     Luo, Z.; Xu, Y.; Ye, E.; Li, Z.*; Wu, Y.-L.*Recent Progress in Macromolecules Anchored Gold Nanoparticle Hybrid System for Therapeutic Applications.Macromolecular Rapid Communications, 2019, 40(5): 1800029. (SCI impact factor: 4.078)

20.     Chen, Y.-P.; Zhang, J.-L.; Zou, Y.; Wu, Y.-L.* “Recent Advances on Polymeric Beads or Hydrogels as Embolization Agents for Improved Transcatheter Arterial Chemoembolization (TACE).” Frontiers in Chemistry, 2019, 7: 408. (SCI impact factor: 3.782)

21.     Xu, C.; Wu, Y.-L.*; Li, Z.*; Loh, X. J.* “Cyclodextrin-Based Sustained Gene Release Systems: A Supramolecular Solution towards Clinical Applications.” Materials Chemistry Frontiers, 2019, 3(2): 181-192.(SCI impact factor: 6.788)

22.     Luo, Z.; Wu, Y.-L.*; Li, Z.*; Loh, X. J.* “Recent Progress in Polyhydroxyalkanoates-Based Copolymers for Biomedical Applications.” Biotechnology Journal, 2019, 14(12): 1900283. (SCI impact factor: 3.543)

23.     Chen, K.; Jiang, S.; Hong, Y.; Li, Z.*; Wu, Y.-L.*; Wu, C.* Cationic Polymeric Nanoformulation: Recent Advances in Material Design for CRISPR/Cas9 Gene Therapy.Progress in Natural Science: Materials International, 2019, 29(6): 617-627. (SCI impact factor: 3.310)

24.     Xue, K.; Wang, X.; Yong, P. W.; Wu, Y.-L.*; Li, Z.*; Loh, X. J.* “Hydrogels as Emerging Materials for Translational Biomedicine.” Advanced Therapeutics, 2019, 2(1): 1800088.

25.     Jiang, L.; Luo, Z.; Loh, X. J.*; Wu, Y.-L.*; Li, Z.* “PHA-Based Thermogel as a Controlled Zero-Order Chemotherapeutic Delivery System for the Effective Treatment of Melanoma.” ACS Applied Bio Materials, 2019, 2(8): 3591-3600.

26.     Li, W.; Xu, C.; Li, S.; Chen, X.; Fan, X.; Hu, Z.; Wu, Y.-L.*; Li, Z.* “Cyclodextrin Based Unimolecular Micelles with Targeting and Biocleavable Abilities as Chemotherapeutic Carrier to Overcome Drug Resistance.” Materials Science and Engineering: C, 2019, 105: 110047. (SCI impact factor: 4.959)

27.     Guan, G.; You, M.; Liu, X.; Wu, Y.-L.*; Ye, E.*; Li, Z.* “Tris-Stabilized MoS2 Nanosheets with Robust Dispersibility and Facile Surface Functionalization.” Advanced Materials Interfaces, 2019, 6(12): 1900585. (SCI impact factor: 4.713)

28.     Han, L.-Y.; Wu, Y.-L.; Zhu, C.-Y.; Wu, C.-S.*; Yang, C.-R.* “Improved Pharmacokinetics of Icariin (ICA) within Formulation of PEG-PLLA/PDLA-PNIPAM Polymeric Micelles.” Pharmaceutics, 2019, 11(2): 51. (SCI impact factor: 4.773)

29.     Kumar, J. N.*; Wu, Y.-L.; Loh, X. J.; Ho, N. Y.; Aik, S. X.; Pang, V. Y. “The Effective Treatment of Multi-Drug Resistant Tumors with Self-Assembling Alginate Copolymers.” Polymer Chemistry, 2019, 10(2): 278-286. (SCI impact factor: 4.760)

30.     Lui, Y. S.; Sow, W. T.; Tan, L. P.*; Wu, Y.-L.; Lai, Y.; Li, H.* “4D Printing and Stimuli-responsive Materials in Biomedical Applications.” Acta Biomaterialia, 2019, 92: 19-36. (SCI impact factor: 6.638)

31.     Zhu, C.; Chen, Z.; Gao, S.; Goh, B.; Samsudin, I.; Lwe, K.; Wu, Y.-L.; Wu C.; Su, X.* Recent Advances in Non-Toxic Quantum Dots and Their Biomedical Applications.Progress in Natural Science: Materials International, 2019, 29(6): 628-640. (SCI impact factor: 3.310)

32.     Wang, T.;  Qi, D.;  Yang, H.; Liu, L.; Wang, M.; Leow, W. R.; Chen, G.; Yu, J.; He, K.; Cheng, H.; Wu, Y.-L.; Zhang, H.*; Chen, X.* “Tactile Chemomechanical Transduction Based on an Elastic Microstructured Array to Enhance the Sensitivity of Portable Biosensors.” Advanced Materials, 2019, 31(1): 1803883. (SCI impact factor: 25.809)

33.     Cai, P.; Li, Z.; Keneth, E. S.; Wang, L.; Wan, C.; Jiang, Y.; Hu, B.; Wu, Y.-L.; Wang, S.; Lim, C. T.; Makeyev, E. V.; Magdassi, S.*; Chen, X.* “Differential Homeostasis of Sessile and Pendant Epithelium Reconstituted in a 3D-Printed “GeminiChip”.” Advanced Materials, 2019, 31(28): 1900514. (SCI impact factor: 25.809)

2018

34.     Luo, Z.; Jiang, L.; Ding, C.; Hu, B.; Loh, X. J.; Li, Z.*; Wu, Y.-L.*Surfactant Free Delivery of Docetaxel by Poly[(R)-3-hydroxybutyrate-(R)-3-hydroxyhexanoate]-Based Polymeric Micelle for Effective Melanoma Treatments.Advanced Healthcare Materials, 2018, 7(23): 1801221. (SCI impact factor: 5.609)

35.     Cheng, H.; Fan, X.; Wang, X.; Ye, E.; Loh, X. J.*; Li, Z.*; Wu, Y.-L.*Hierarchically Self-Assembled Supramolecular Host-Guest Delivery System for Delivery of Chemotherapeutics to Drug Resistant Cancer Tumors.Biomacromolecules, 2018, 19(6): 1926-1938. (SCI impact factor: 5.738)

36.     Cheng, H.; Wu, Z.; Wu, C.; Wang, X.; Liow, S. S.;Li, Z.; Wu, Y.-L.* Overcoming STC2 Mediated Drug Resistance Through Drug and Gene Co-delivery by PHB-PDMAEMA Cationic Polyester in Liver Cancer Cells.Materials Science and Engineering: C, 2018, 83: 210-217. (SCI impact factor: 5.080)

37.     Chen,  X.; Chen, Z.; Hu, B.; Cai, P.; Wang, S.; Xiao, S.; Wu, Y.-L.*; Chen, X.* Synergistic Lysosomal Activatable Polymeric Nanoprobe Encapsulating pH Sensitive Imidazole Derivative for Tumor Diagnosis.Small, 2018, 14(9): 1703164. [Highlighted by Materials Views China: http://www.materialsviewschina.com/2018/02/27859/] (SCI impact factor: 9.598)

38.     Fan, X.; Cheng, H.; Wang, X.; Ye, E.; Loh, X. J.; Wu, Y.-L.*; Li, Z.* “Thermo-responsive Supramolecular Chemotherapy by “V”-shape Armed b-Cyclodextrin Star Polymer to Overcome Drug Resistance.” Advanced Healthcare Materials, 20187(7): 1701143. (SCI impact factor: 5.609)

39.     Liu, X.; Fan, X.; Jiang, L.; Loh, X. J.; Wu, Y.-L.*; Li, Z.* “Biodegradable Polyester Unimolecular Systems as Emerging Materials for Therapeutic Applications.” Journal of Materials Chemistry B, 2018, 6(35): 5488-5498. (SCI impact factor: 4.776)

40.     Fan, X.; Cheng, H.; Wu, Y.; Loh, X. J.*; Wu, Y.-L.*; Li, Z.* “Incorporation of Polycaprolactone to Cyclodextrin-based Nanocarrier for Potent Gene Delivery.” Macromolecular Materials and Engineering, 2018, 303(9): 1800255. (SCI impact factor: 2.690)

41.     Chan, B.Q.Y.; Cheng, H.; Liow, S.S.; Dou, Q.; Wu, Y.-L.*; Loh, X.J.*; Li, Z.* “Poly(carbonate urethane)-Based Thermogels with Enhanced Drug Release Efficacy for Chemotherapeutic Applications.” Polymers, 2018, 10(1): 89. (SCI impact factor: 2.935)

42.     Wang, X.; Young, D. J.; Wu, Y.-L.*; Loh, X. J.* “Thermogelling 3D Systems towards Stem Cell-Based Tissue Regeneration Therapies.” Molecules, 2018, 23(3): 553. (SCI impact factor: 3.098)

43.     Cai, P.; Zhang, X.; Wang, M.; Wu, Y.-L.; Chen, X.* “Combinatorial Nano−Bio Interfaces.” ACS Nano, 2018, 12(6): 5078-5084. (SCI impact factor: 13.709)

44.     Wojnilowicz, M.; Besford, Q. A.; Wu, Y.-L.; Loh, X. J.; Braunger, J. A.; Glab, A.; Cortez-Jugo, C.; Caruso, F.*; Cavalieria, F.* “Glycogen-Nucleic Acid Constructs for Gene Silencing in Multicellular Tumor Spheroids.” Biomaterials, 2018, 176: 34-49. (SCI impact factor: 8.806)

45.     Shan, W.; Zhang, D.; Wu , Y.-L.; Lv, X.; Hu, B.; Zhou, X.; Ye, S.; Bi, S.; Ren, L.*; Zhang, X.* “Modularized Peptides Modified HBc Virus-Like Particles for Encapsulation and Tumor-Targeted Delivery of Doxorubicin.” Nanomedicine: Nanotechnology, Biology and Medicine, 2018, 14(3): 725-734. (SCI impact factor: 6.500)

46.     Cai, P.; Hu, B.; Leow, W. R.; Wang, X.; Loh, X. J.; Wu, Y.-L.; Chen, X.* “Biomechano-Interactive Materials and Interfaces.” Advanced Materials, 2018, 30(31): 1800572. (SCI impact factor: 21.950)

47.     Hu, B.; Owh, C.; Chee, P. L.; Leow, W. R.; Liu, X.; Wu, Y.-L.; Guo, P.; Loh, X. J.*; Chen X.* “Supramolecular Hydrogels for Antimicrobial Therapy.” Chemical Society Reviews, 2018, 47(18): 6917-6929. (SCI impact factor: 40.182)

2017

48.     Wu, Y.-L.; Engl, W.; Hu, B.; Cai, P.; Leow, W. R.; Tan, N. S.; Lim, C. T.; Chen, X.* “Nanomechanically Visualizing Drug-Cell Interaction at the Early Stage of Chemotherapy.ACS Nano, 2017, 11(7): 6996-7005. (SCI impact factor: 13.942)

49.     Cai, P.; Leow, W. R.; Wang, X.; Wu, Y.-L.*; Chen, X.* “Programmable Nano-Bio Interfaces for Functional Biointegrated Devices.” Advanced Materials, 2017, 29(26): 1605529. [Featured as Inside Back Cover] [Highlighted by Materials Views China: http://www.materialsviewschina.com/2017/05/24998/] (SCI impact factor: 19.791)

50.     Liu, X.; Chen, X.; Chua, M. X.; Li, Z.*; Loh, X. J.*; Wu, Y.-L.*Injectable Supramolecular Hydrogels as Delivery Agents of Bcl-2 Conversion Gene for the Effective Shrinkage of Therapeutic Resistance Tumors.Advanced Healthcare Materials, 2017, 6(11): 1700159. [Featured as Front Cover] [Highlighted by Advanced ScienceNews: http://www.advancedsciencenews.com/cover-art-featuring-cancer-therapy-angiogenesis-tissue-engineering/] [Highlighted by Materials Views China: http://www.materialsviewschina.com/2017/07/25828/] (SCI impact factor: 5.110)

51.     Wang, X.;  Liow, S. S.; Wu, Q.; Li, C.; Owh, C.; Li, Z.*; Loh, X. J.*; Wu, Y.-L.* Codelivery for Paclitaxel and Bcl-2 Conversion Gene by PHB-PDMAEMA Amphiphilic Cationic Copolymer for Effective Drug Resistant Cancer Therapy.Macromolecular Bioscience, 2017, 17(11): 1700186. (SCI impact factor: 3.238)

52.     Li, Z.*; Liu, X.; Chen, X.; Chua, M. X.; Wu, Y.-L.*Targeted Delivery of Bcl-2 Conversion Gene by MPEG-PCL-PEI-FA Cationic Copolymer to Combat Therapeutic Resistant Cancer.Materials Science and Engineering: C, 2017, 76: 66-72. (SCI impact factor: 4.164)

53.     Yang, D.-P.; Liu, X.; Teng, C. P.; Owh, C.; Win, K. Y.; Lin, M.; Loh, X. J.; Wu, Y.-L.*; Li, Z.; Ye, E.* Unexpected Formation of Gold Nanoflowers by a Green Synthesis Method as Agents for a Safe and Effective Photothermal Therapy.Nanoscale, 2017, 9(41): 15753–15759. (SCI impact factor: 7.367)

54.     Liow, S. S.; Dou, Q.; Kai, D.; Sugiarto S.; Yu, C. Y. Y.; Kwok, R. T. K.; Chen, X.; Wu, Y.-L.*; Ong, S. T.; Kizhakeyil, A.; Verma N. K.; Tang, B. Z.; Loh, X. J.* “Long-term Real-time in vivo Drug Release Monitoring with AIE Thermogelling Polymer.” Small, 2017, 13(7): 1603404. [Featured as Back Cover] (SCI impact factor: 8.643)

55.     Zheng, C.; Gao, H.; Yang, D.-P.*; Liu, M.; Cheng, H.; Wu, Y.-L.*; Loh, X. J.*PCL-based Thermo-gelling Polymers for In Vivo Delivery of Chemotherapeutics to Tumors.Materials Science and Engineering: C, 2017, 74: 110-116. (SCI impact factor: 4.164)

56.     Fan, X.; Wang, X.; Cao, M.; Wang, C.; Hu, Z.; Wu, Y.-L.*;Li, Z.*; Loh, X. J.Y-Shape Armed Amphiphilic Star-like Copolymer: Design, Synthesis and Dual-Responsive Unimolecular Micelle Formation for Controlled Drug Delivery.Polymer Chemistry, 2017, 8(36): 5611-5620. (SCI impact factor: 5.375)

57.     Hu, B.; Leow, W. R.; Cai, P.; Li, Y.-Q.; Wu, Y.-L.; Chen, X.* “Nanomechanical Force Mapping of Restricted Cell-To-Cell Collisions Oscillating between Contraction and Relaxation.” ACS Nano, 2017, 11(12): 12302-12310. (SCI impact factor: 13.709)

58.     Wang, P.; Zeng, W.; Liu, J.; Wu, Y.-L.; Ma, Y.; Zeng, Z.; Pang, J.-y.*; Zhang, X.-k.; Yan, X.; Wong, A.; Zeng, J.-Z.* “TRC4, an Improved Triptolide Derivative, Specifically Targets to Truncated Form of Retinoid X Receptor-alpha in Cancer Cells.” Biochemical Pharmacology, 2017, 124: 19-28. (SCI impact factor: 4.581)

59.     Li, J.-F.; Yan, X.; Wu, Y.-L.; Fang, M.-J.; Wu, Z.; Qiu, Y.-K.* “Comprehensive Two-dimensional Normal-phase Liquid Chromatography ´ Reversed-phase Liquid Chromatography for Analysis of Toad Skin.” Analytica Chimica Acta, 2017, 962: 114-120. (SCI impact factor: 4.950)

60.     Zeng W.; Zhang, C.; Cheng, H.; Wu, Y.-L.; Liu, J.; Chen, Z.; Huang, J. G.; Ericksen, R. E.; Chen, L.; Zhang, H.; Wong, A. S.*; Zhang, X.-k.; Han, W.; Zeng, J.-Z.* “Targeting to the Non-genomic Activity of Retinoic Acid Receptor-Gamma by Acacetin in Hepatocellular Carcinoma.” Scientific Reports, 2017, 7: 348. (SCI impact factor: 4.259).

61.     Hu, B.; Leow, W. R.; Amini, S.;  Nai, B.; Zhang, X.; Liu, Z.; Cai, P.; Li, Z.; Wu, Y.-L.; Miserez, A.; Lim, C. T.; Chen, X.* “Orientational Coupling Locally Orchestrates a Cell Migration Pattern for Re-Epithelialization.” Advanced Materials, 2017, 29(29): 1700145. (SCI impact factor: 19.791)

62.     Wee, C. Y.; Liow, S. S.; Li, Z.; Wu, Y.-L.; Loh, X. J.* “New Poly[(R)-3-hydroxybutyrate-co-4-hydroxybutyrate] (P3HB4HB)-Based Thermogels.” Macromolecular Chemistry and Physics, 2017, 218(17): 1700196. (SCI impact factor: 2.500)

63.     Wang, Y.-Q.; Tang, X.; Li, J.-F.; Wu, Y.-L.; Sun, Y.-Y.; Fang, M.-J.; Wu, Z.; Wang, X.-M.*; Qiu, Y.-K.*Development of an On-Line Mixed-Mode Gel Liquid Chromatography × Reversed Phase Liquid Chromatography Method for Separation of Water Extract from Flos Carthami.Journal of Chromatography A, 2017, 1519: 145-151. (SCI impact factor: 3.981)

2016 and before

64.     Chen, X.; Qiu, Y.-K.; Owh, C.; Loh, X. J.*; Wu, Y.-L.* “Supramolecular Cyclodextrin Nanocarriers for Chemo- and Gene Therapy towards the Effective Treatment of Drug Resistant Cancers.” Nanoscale, 2016, 8(45): 18876-18881. (SCI impact factor: 7.367)

65.     Wu, Y.-L.*; Wang, H.; Qiu, Y.-K.; Liow, S. S; Li, Z.; Loh, X. J.* “PHB-based Gels as Delivery Agents of Chemotherapeutics for the Effective Shrinkage of Tumors.” Advanced Healthcare Materials, 2016, 5(20): 2679-2685. [Highlighted by http://www.advancedsciencenews.com/injectable-hydrogels-for-precise-chemotherapy/] (SCI impact factor: 5.110)

66.     Wu, Y.-L.*; Wang, H.; Qiu, Y.-K.; Loh, X. J.* “PLA-based Thermogel for the Sustained Delivery of Chemotherapeutics in a Mouse Model of Hepatocellular Carcinoma.” RSC Advances, 2016, 6(50): 44506-44513. (SCI impact factor: 3.108)

67.     Li, J.-F.; Fang, H.; Yan, X.; Chang, F.-R.; Wu, Z.; Wu, Y.-L.*; Qiu, Y.-K.* “On-line Comprehensive Two-dimensional Normal-phase Liquid Chromatography × Reversed-phase Liquid Chromatography for Preparative Isolation of Toad Venom.” Journal of Chromatography A, 2016, 14556(22): 169-175. (SCI impact factor: 3.981)

68.     Lin, N.; Chen, X.; Yan, S.; Wang, H.; Lu, Z.; Xia, X.; Liang, M.; Wu, Y.-L.*; Zheng, L.*; Cao Q.*; Ding, Z. “An Aggregation-Induced Emission Based pH-sensitive Fluorescent Probe for Intracellular Acidity Sensing.” RSC Advances, 2016, 6(30): 25416-25419. (SCI impact factor: 3.108)

69.     Wu, Y.-L.; Chen, X.; Wang, W.; Loh, X. J.* “Engineering Bioresponsive Hydrogels towards Healthcare Applications.” Macromolecular Chemistry and Physics, 2016, 217(2): 175-188. [Featured in Front Cover] (SCI impact factor: 2.500)

70.     Cai, P.; Layani, M.; Leow, W. R.; Amini, S.; Liu, Z.; Qi, D.; Hu, B.; Wu, Y.-L.; Miserez, A.; Magdassi, S.; Chen, X.* “Bio-Inspired Mechanotactic Hybrids for Orchestrating Traction-Mediated Epithelial Migration.” Advanced Materials, 2016, 28(16): 3102-3110. (SCI impact factor: 19.791)

71.     Yan, X.; Wang, L.-J.; Wu, Z.; Wu, Y.-L.; Liu, X.-X.; Chang, F.-R.; Fang, M.-J.*; Qiu, Y.-K.* “New On-Line Separation Workflow of Microbial Metabolites via Hyphenation of Analytical and Preparative Comprehensive Two-Dimensional Liquid Chromatography.” Journal of Chromatography B, 2016, 1033-1034: 1-8. (SCI impact factor: 2.603)

72.     Tay, C. Y.*; Wu, Y.-L.; Cai, P.; Tan, N. S.; Venkatraman, S. S.; Chen, X.; Tan, L. P.* “Bio-inspired Micropatterned Hydrogel to Direct and Deconstruct Hierarchical Processing of Geometry-force Signals by Human Mesenchymal Stem Cells during Smooth Muscle Cell Differentiation.” NPG Asia Materials, 2015, 7(7): e199. (SCI impact factor: 9.157)

73.     Chen, W.-B.; Li, S.-Q.; Chen, L.-J.; Fang, M.-J.; Chen, Q.-C.; Wu, Z.; Wu, Y.-L.*; Qiu, Y.-K.* “Online Polar Two Phase Countercurrent Chromatography × High Performance Liquid Chromatography for Preparative Isolation of Polar Polyphenols from Tea Extract in a Single Step.” Journal of Chromatography B, 2015, 997: 179-186. (SCI impact factor: 2.603)

74.     Loh, X. J.*; Wu, Y.-L. “Cationic Star Copolymers Based on β-Cyclodextrins for Efficient Gene Delivery to Mouse Embryonic Stem Cell Colonies.” Chemical Communications, 2015, 51(54): 10815-10818. [Featured in Back Cover] (SCI impact factor: 6.319)

75.     Wang, D.; Chen, L.-J.; Liu, J.-L.; Wang, X.-Y.; Wu, Y.-L.; Fang, M.-J.; Wu, Z.; Qiu, Y.-K.* “On-line Two-dimensional Countercurrent Chromatography × High Performance Liquid Chromatography System with a Novel Fragmentary Dilution and Turbulent Mixing Interface for Preparation of Coumarins from Cnidium monnieri.” Journal of Chromatography A, 2015, 1406: 215-223. (SCI impact factor: 3.981)

76.     Hu, B.; Shi, W.; Wu, Y.-L.; Leow, W. R.; Cai, P.; Li, S.; Chen, X.* “Orthogonally Engineering Matrix Topography and Rigidity to Regulate Multicellular Morphology.” Advanced Materials, 2014, 26(33): 5786-5793. (SCI impact factor: 19.791)

77.     Yin, S.; Wu, Y.-L.; Hu, B.; Wang, Y.; Cai, P.; Tan, C. K.; Qi, D.; Zheng, L.; Leow, W. R.; Tan, N. S.; Wang, S.; Chen, X.* “Three-dimensional Graphene Composite Macroscopic Structures for Capture of Cancer Cells.” Advanced Materials Interfaces,2014, 1(1): 1300043. (SCI impact factor: 4.279)

78.     Liu, J.-L.; Wang, X.-Y.; Zhang, L.-L.; Fang, M.-J.; Wu, Y.-L.; Wu, Z.; Qiu, Y.-K.* “Two-dimensional Countercurrent Chromatography × High Performance Liquid Chromatography with Heart-cutting and Stop-and-go Techniques for Preparative Isolation of Coumarin Derivatives from Peucedanum praeruptorum Dunn.” Journal of Chromatography A, 2014, 1374 : 156–163. (SCI impact factor: 3.981)

79.     Wu, Y.-L.; Putcha, N.; Ng, K.W.; Leong, D.; Lim, C.T.; Loo, S.C.; Chen, X.* “Biophysical Responses upon the Interaction of Nanomaterials with Cellular Interfaces.” Accounts of Chemical Research, 2013, 46(3):782-791. (SCI impact factor: 20.268)

80.     Wu, Y.-L.; Yin, H.; Zhao, F.; Li, J.* “Multifunctional Hybrid Nanocarriers Consisting of Supramolecular Polymers and Quantum Dots for Simultaneous Dual Therapeutics Delivery and Cellular Imaging.” Advanced Healthcare Materials, 2013, 2(2): 297-301. (SCI impact factor: 5.110)

81.     Lam, C.R.; Tan, C.; Teo, Z.; Tay, C.Y.; Phua, T.; Wu, Y.-L.; Cai, P.Q.; Tan, L.P.; Chen, X.; Zhu, P.; Tan, N.S.* “Loss of TAK1 Increases Cell Traction Force in a ROS-dependent Manner to Drive Epithelial-Mesenchymal Transition of Cancer Cells.” Cell Death & Disease, 2013, 4: e848. (SCI impact factor: 5.965)

82.     Cai, L.L.; Ye, H.M.; Lv, X.N.; Wu, Y.-L.; Zhang, H.J.; Zheng, L.M.; Tzeng, C.M.* “25-(OH)VitD3, as a Risk Indicator in Diagnosis of Adenocarcinoma.” Current Drug Targets, 2013, 14(11): 1367-1376. (SCI impact factor: 3.236)

83.     Wu, D.-C.*; Loh, X.J.; Wu, Y.-L.; Lay, C.L.; Liu, Y.*’Living’ Controlled in situ Gelling Systems: Thiol-Disulfide Exchange Method toward Tailor-Made Biodegradable Hydrogels.Journal of the American Chemical Society, 2010, 132(43): 15140-1514. (SCI impact factor: 13.858)

84.     Loh, X.J.*; Zhang, Z.-X.; Mya, K.Y.; Wu, Y.-L.; He, C.B.; Li, J.*Efficient Gene Delivery with Paclitaxel-Loaded DNA-Hybrid Polyplexes Based on Cationic Polyhedral Oligomeric Silsesquioxanes.Journal of Materials Chemistry, 2010, 20(47): 10634-10642. (SCI impact factor: 6.101)

85.     Wu, Y.-L.; Li, J.*Synthesis of Supramolecular Nanocapsules Based on Threading Multiple Cyclodextrins over Polymer on Gold Nanoparticles.Angewandte Chemie International Edition, 2009, 48(21): 3842-3845. [Highlighted by Nature Asia-Pacific: http://www.nature.com/am/journal/2009/200908/full/am2009185a.html] (SCI impact factor: 11.994)

86.     Loh, X.J.; Zhang, Z.-X.; Wu, Y.-L.; Lee, T.S.; Li, J.*Synthesis of Novel Biodegradable Thermoresponsive Triblock Copolymers Based on Poly[(R)-3-hydroxybutyrate] and Poly(N-isopropylacrylamide) and Their Formation of Thermoresponsive Micelles.Macromolecules, 2009, 42(1): 194-202. (SCI impact factor: 5.835)

87.     Loh, X.J.; Wu, Y.-L.; Seow, W.T.J.; Norimzan, M.N.I.; Zhang, Z.-X.; Xu, F.-J.; Kang, E.-T.; Neoh, K.-G.; Li, J.*Micellization and Phase Transition Behavior of Thermosensitive Poly(N-isopropylacrylamide)–Poly(e-caprolactone)–Poly(N-isopropylacrylamide) Triblock Copolymers.Polymer, 2008, 49(23): 5084-5094. (SCI impact factor: 3.684)

88.     Cui, H.*; Zhang, Z.-F.; Shi, M.-J.; Xu, Y.; Wu, Y.-L.Light Emission of Gold Nanoparticles Induced by the Reaction of Bis(2,4,6-trichlorophenyl) Oxalate and Hydrogen Peroxide.Analytical Chemistry, 2005, 77(19): 6402-6406. (SCI impact factor: 6.320)

Book Chapters

1. Luo, R.-C.; Wu, Y.-L.; EI-Newehy, M. ²The Industrial Production of PHA.² A Chapter in ²Polyhydroxyalkanoates (PHAs): Biosynthesis, Industrial Production and Applications in Medicine.² (Edited by L.-P. Wu) NOVA Science Publishers, ISBN: 978-1-63321-659-4, 2014, 133-140.

2. Luo, R.-C.; Wu, Y.-L.; EI-Newehy, M. ²Extraction and Purification of Polyhydroxyalkanoates.² A Chapter in ²Polyhydroxyalkanoates (PHAs): Biosynthesis, Industrial Production and Applications in Medicine.² (Edited by L.-P. Wu) NOVA Science Publishers, ISBN: 978-1-63321-659-4, 2014, 141-152.

3. Chen, K.; Yang, J.; Guo, S.; Chen, C.-H.; Luo, R.-C.; Wu, Y.-L.²Hydrogel Coatings for Heart Stents.² Materials Science and Technology (Wiley-VCH Verlag GmbH & Co. KGaA), 2019, DOI: 10.1002/9783527603978.mst0490.

 

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