生物医学研究院学术报告

发布者:系统管理员 发布时间:2010-12-06 浏览次数:

The Roles of FRS2alpha in Prostate Development and Tumorigenesis

Dr. Zhang Yongyou (张永有)博士

Center for Cancer and Stem Cell Biology

Instituteof Biosciencesand Technology

TexasA&M University Health Sciences Center

Houston, TX 77030, USA.

20081031日(星期五)3:30pm-5:00pm

卢嘉锡楼二楼会议室

相关论文:

1. Y. Zhang, Y. Lin, C. Bowles, and F. Wang (2004). Direct cell cycle regulation by the fibroblast growth factor receptor (FGFR) kinase through phosphorylation-dependent release of Cks1 from FGFR substrate 2, Journal of Biological Chemistry.31:379(53)

2. Y. Zhang, J. Zhang, Y. Lin, Y. Lan, C. Lin, J.W. Xuan, M.M. Shen, W.L. McKeehan, N.M. Greenberg, and F. Wang (2008). Role of epithelial cell fibroblast growth factor receptor substrate 2alpha in prostate development, regeneration and tumorigenesis. Development. 135(4):775-84.

3. Y. Zhang, K. McKeehan, Y. Lin, J. Zhang, and F. Wang (2008).FGFR1 tyrosine phosphorylation regulates binding of FRS2alpha but not FRS2beta to the receptor. Molecular Endocrinology. 22(1):167-75

4. V. D. Acevedo, R. D. Gangula, R. Li,Y. Zhang, F. Wang, G.E. Ayala, L.E. Peterson, M. Ittmann, and D.M. Spencer (2007). Inducible FGFR-1 activation leads to irreversible prostate adenocarcinoma and an epithelial to mesenchymal transition. Cancer Cell.12(6):559-571.