PI：朱铉博士、教授，博士生导师，厦门大学药学院副院长
教育背景：
1998.8—2001.7吉林省延边大学药剂专业 硕士
2001.8—2005.8韩国首尔大学药科大学药学专业 博士
2005.9—2006.11 韩国首尔大学药科大学博士后研究员
现任福建省药剂专业委员会常务委员、福建省高校新世纪优秀人才、福建省食品安全促进会专家组成员、“厦门大学黄大年式教师团队”骨干成员。Molecules, Drug Delivery, International Journal of Science, International Journal of Pharmaceutics, Journal of Pharmaceutical Science, NanoResearch等杂志的审稿人。
主要研究方向：
(1)肿瘤靶向药物递送研究；(2)纳米药物诊疗一体化研究；(3)体内代谢研究；
研究成果：
近年来，以通讯及第一作者发表学术论文30余篇，作为主要发明人申请发明专利2项。主持国家级面上、省级课题3项，厦门市课题2项，多项横向课题。
近期发表论文：
1.Jinyuan Ma, HOngjie Wu, Yang Li, Zehua Liu, Guihua Liu, Yuxin Guo, Zhenqing Hou, Qingliang Zhao, Dengyue Chen*, Xuan Zhu*. Novel Core-Interlayer-Shell DOX/ZnPc Co-Loaded MSN@pH-Sensitive Cap@PEGylated Liposome for Enhanced Synergetic Chemo-Photodynamic Therapy. Pharmaceutical Research, 2018,35(3):57.（封面期刊）
2.Jinyuan Ma, Yang Li, Guihua Liu, Ai Li, Yilin Chen, Xinyi Zhou, Dengyue Chen, Zhenqing Hou*, Xuan Zhu∗. Novel theranostic zinc phthalocyanine–phospholipid complex self-assembled nanoparticles for imaging-guided targeted photodynamic treatment with controllable ROS production and shape-assisted enhanced cellular uptake. Colloids and Surfaces B: Biointerfaces,162 (2018) 76–89.（封面期刊）
3.Yuxin Guo, Yang Zhang, Jinyuan Ma, Qi Li, Yang Li, Xinyi Zhou, Dan Zhao, Hua Song, Qing Chen*, Xuan Zhu*. Light/magnetic hyperthermia triggered drug released from multifunctional thermo-sensitive magnetoliposomes for precise cancer synergetic theranostics. Journal of Controlled Release.2018(272):145-158.
4.Yang Li*, Liang Song, Jinyan Lin, Jinyuan Ma, Zhou Pan, Yinying Zhang, Guanghao Su, Shefang Ye, Fanghong Luo, Xuan Zhu, Zhenqing Hou*. Programmed nanococktail based on pH-responsive function switch for self-synergistic tumor-targeting therapy. ACS App;ied materials & interfaces. 2017,9, 39127-39142.
5.Yang Li, Jinyan Lin, Jinyuan Ma, Liang Song, Huirong Lin, Bowen Tang, Dengyue Chen, Guanghao Su, Shefang Ye, Xuan Zhu, Fanghong Luo*, Zhenqing Hou*. Methotrexate-Camptothecin prodrug Nanoassemblies as a Versatile Nanoplatform for Biomodal Imaging-Guided Self-Active Targeted and Synergistic Chemotherapy. ACS Appl. Mater. Interfaces. 2017, 9, 34650−34665.
6.Yang Li, Guihua Liu, Jingyuan Ma, Jinyan Lin, Huirong Lin, Guanghao Su, Deyue Chen, Shefang Ye, Xiaoyuan Chen, Xuan Zhu*, Zhenqing Hou*. Chemotherapeutic drug-photothermal agent co-self-assembling nanoparticles for near-infrared fluorescence and photoacoustic dual-modal imaging-guided chemo-photothermal synergistic therapy. Journal of Controlled Release. 2017,258(28):5-107.
7.Guihua Liu, Jinyuan Ma, Yang Li, Qi Li, Chunhua Tan, Hua Song, Shuhui Cai, Zhenqing Hou, Qing Chen*, Xuan Zhu*. Core-interlayer-shell Fe3O4@mSiO2@ lipid-PEG-methotrexate nanoparticle for multimodal imaging and multistage targeted chemo-photodynamic therapy, International Journal of Pharmaceutics, 2017, 521:19-32
8.Yang Li, Jinyan Lin, Guihua Liu, Jinyuan Ma, Liya Xie, Fuqiang Guo, Xuan Zhu*, Zhenqing Hou*, Dual-acting, function-responsive, and high drug payload nanospheres for combining simplicity and efficacy in both self-targeted multi-drug co-delivery and synergistic anticancer effect, International Journal of Pharmaceutics, 2016, 512:194–203
9.Qing Chen, Jianhong Lin，Dan Zhao，Xuan Zhu*, Isolation and Stucture Elucidation of Diterpenes from Wedelia prostrata and Their Cytotoxicity Activities, Chemical Research in Chinese Universities, 2016, 32(5) :792-796
10.Yanxiu Li, Jinyan Lin, Guihua Liu, Yang Li, Liang Song, Zhongxiong Fan, Xuan Zhu, Guanghao Su*, Zhengqing Hou*, Self-assembly of multifunctional integrated nanoparticles loaded with a methotrexate-phospholipid comlex: combining simplicity and efficacy in both targeting and anticancer effects, RSC Advances, 2016, 6(89):86717-86727
11.Hua Song, Jianhong Lin, Xuan Zhu, Qing Chen*, Developments in high-speed countercurrent chromatography and its applications in the separation of terpenoids and saponins，Journal of Separation Science, 2016, 39(8) : 1574-1591
12.Jing Lin, Hongjie Wu, Yingjun Wang, Jianhong Lin, Qing Chen, Xuan Zhu*, Preparation and Ocular Pharmacokinetics of Hyaluronan Acid Modified Mucoadhesive Liposomes, Drug Delivery, 2016, 23(4):1144-1151.
13.ZhiRan Xu, Wufang Wang, Xinfang Liang, Zehua Liu, Yu Liu, Liang Lin, Xuan Zhu*, Protective Effects of Poly (butyl) Cyanoacrylate Nanoparticles Containing Vasoactive Intestinal Peptide Against 6-Hydroxydopamine-Induced Neurotoxicity In Vitro, Journal of Molecular Neuroscience, 2015, 55(4):854-864
14.Xianhua Zhang, Yueping Wu, Xuan Zhu*, Ying Hong, Liang Lin, Qingjiang Lin, Preparation and evaluation of dl-praeruptorin A microemulsion based hydrogel for dermal delivery, Drug Delivery, 2015, 22(6):757-764
15.Zehua Liu, Shaoheng Tang, Ziran Xu, Yingjun Wang, Xuan Zhu, Liangcheng Li, Wanjin Hong, Xiumin Wang, Preparation and in vitro, evaluation of a multifunctional iron silicate@liposome nanohybrid for ph-sensitive doxorubicin delivery and photoacoustic imaging. Journal of Nanomaterials, 2015(2):1-13.
联系方式：
地址：福建省厦门市翔安区翔安南路厦门大学药学院
邮编：361102
电话：0592-2881181
Email:zhuxuan@xmu.edu.cn
