Chi-Meng Tzeng, Ph.D.
Dr. Tzeng received comprehensively graduated training in National Tsin-Hua University (Nuclear Science School in Radiation Biology,, advised by Dr. Rong-Long Pan, in 1989~1993) and Stanford University (Medical School in Biochemistry, advised by Dr. Arthur Kornberg, Nobel Prize Laureate, in 1995~1999). Moreover, he also expansively practiced either academic professorship or industrial executive position from Academic Sinica (Instit. of BioAgricultural Science), National Taiwan University Hospital (Dept. of Biomedical Research), U-Vision Biotech, VitaGenomics/GeneCore, MaxyBio to Beckman Coulter from 2000 to 2010.
Dr. Tzeng enjoys fully skills of protein chemistry, biochemistry, -omics and translation medicine holding more than 30 peer-reviewed SCI/IE scientific articles with cited frequency as 323 from 1995 to 2010, 3 book chapters, 4 pending patents and in excess of 6 commercialized diagnostic products. He is interesting in pooling biomedical research, marketing analysis, financial manipulation and entrepreneur atmosphere to generate biomedical outcomes of commercialization.
Recently, Dr. Tzeng is leading clinical resources, academic force and bio-industrial energy to decipher the biomarkers, molecular mechanism and personalized theranostics from projects of adenocarcinoma (EGFR signaling pathways), leukemia (A/C-M/L-L fusion genes), leukoaraiosis (LA, genetic diagnosis or prognosis), mesenchymal stem cell (mass expansion) and aromatherapy (terpenoids and 5-HT) at Xiamen University and Torch Hi-Tech Industrial Development zone.
Being a team player of translation medicine, our laboratory strongly collaborates with industries: BioScent Innovation(BSI) in molecular aromatherapy; VivaCell in MSCs expansions; RBC Bioscience in total solution of genetic diagnosis, CYF Biotech in molecular signature of Collocalia and its nest,etc., to benefit the integrated pipelines from academics, society to industry.
1.Chi-chan Chen，Sung-kay Chiu,Chi-meng Tzeng and Wei-chi Ku. Photovoltaic device to accelerate the interaction among biomolecules. U-Vision Biotech Co.,Ltd..US20030077600.
2.Shean-jen Chen,Feng-ming Hsiu,Chien-hung Tsai,Chia-yuan Tsou and Chi-meng Tzeng. Surface plasmon resonance shifting interferometry imaging system for biomolecular interaction analysis. U-Vision Biotech Co.,Ltd. US20030219809.
3.Chi-meng Tzeng, Kung-ming Hsu,Wei-chi Ku,Grace Lau, Jing-tyan Ma and Sung-kay Chiu. Combination of epoxy and amine silanes for immobilizing and hybridizing nucleic acid molecules on a solid support. U-Vision Biotech Co.,Ltd.US20030059819.
4.Chi-chan Chen，Wei-chi Ku，Sung-kay Chiu，Chi-meng Tzeng. Photovoltaic device to accelerate the interaction among biomolecules. U-Vision Biotech Co.,Ltd.WO2003035825.
Selected Publications:（last 5 years）
Xiao Nan Lv, Zhu Jun Liu, Huan Jing Zhang, Chi Meng Tzeng*.Aromatherapyon Central Nerve System (CNS): Therapeutic mechanism and its associated genes. Current Drug Targets.2013,14. (In press. SCI impact factor: 3.553 )
Qilin Ma, Xingkai An, Zhiming Li, Huanjing Zhang, Wenqing Huang, Liangliang Cai, Peng Hu, Qing Lin,Chi-Meng Tzeng*. P268S in NOD2 associates With susceptibility to Parkinson's disease in Chinese Population. Behavioral and Brain Functions. 2013.(In press. SCI Impact factor:2.13)
Zhong-Xian Lv, Wen-Qing Huang, Liang-Liang Cai, Chi-Meng Tzeng* Structure and function of protein tyrosine phosphatase SHP2 (PTPN11) and its role in tumorigenesis. BBA-Reviews on cancer. (Revised. SCI Impact factor :9.380)
Guoyan Liu,Kunhong Liu,Yin Li, Chao Pan, Jiqin Su,Hongfeng Liao,Renxiang Yv, Zhaohui Li, Li Yuan, Huanjing Zhang, Chimeng Tzeng*. Novel cancerization marker,TP53, and its role in distinguishing normal tissue adjacent to cancerous tissue from normal tissue adjacent to benign tissue. World Journal of Surgical Oncology. 2012,10:252. (SCI impact factor: 1.12)
HL Zhang, L Ruan,LM Zheng, Daivid Whyte,CM Tzeng,XW Zhou*. Association between class III β-tubulin expression and response to paclitaxel/vinorbine-based chemotherapy for non-small cell lung cancer: A meta-analysis.Lung cancer. 2012,77(1):9-15. (SCI impact factor: 3.6)
SK Chiu, JT Ma, MH, Hsieh, DL, Lu and CM Tzeng*. Unique Marker Finder Algorithm Generates Molecular Diagnostic Markers. Int.J. Bioinformatics. 2011,7 (1): 24-42.