Jie liu, Ph.D.
Assistant Professor
Experience
Dr. Jie Liu got her Ph.D from Xiamen University in 2004 and 2010. From 2010, she began her postdoctoral research training until 2014.She joined the School of Pharmaceutical Science of Xiamen University as an assistant professor in 2014. She has published high-quality papers in Cancer cell，Cancer Research, Biochemical Pharmacology and so on.
Research
Dr. Liu investigates the regulatory functions of nuclear receptors in physiological and pathological conditions and cellular signal transductions. She also interested in delineates the novel mechanisms of tumor initiation and progression and unravels druggable targets.
Selected Publications (last 5 years):
(1) Qiong-Ying Hu*; Jie Liu*; Xiao-Kun Zhang; Wan-Ting Yang; Yu-Tian Tao; Ce Chen; Ye-He Qian; Jin-Shan Tang; Xin-Sheng Yao; Ying-He Xu; Jing-Hui Wang; Nur77 Serves as a Potential Prognostic Biomarker That Correlates with Immune Infiltration and May Act as a Good Target for Prostate adenocarcinoma. Molecules. 2023;28(3):1238.
(2) Yang Xu; Juanjuan Tian; Qi Kang; Hang Yuan; Chengdong Liu; Zhehui Li; Jie Liu#; Mingyu Li#; Knockout of Nur77 Leads to Amino Acid, Lipid, and Glucose Metabolism Disorders in Zebrafish, Frontiers in Endocrinology, 2022, 13
(3) Qiong-Ying Hu; Xiao-Kun Zhang; Jia-Nan Wang; Hao-Xuan Chen; Lian-Ping He; Jin-Shan Tang; Xin-Sheng Yao; Jie Liu#; Malayoside, a cardenolide glycoside extracted from Antiaris toxicaria Lesch, induces apoptosis in human non-small lung cancer cells via MAPK-Nur77 signaling pathway. Biochem Pharmacol. 2021,190:114622.
(4) Ji Xia; Qiang Luo; Shengbin Huang; Fuquan Jiang; Lin Wang; Guanghui Wang; Jingjing Xie; Jie Liu#; Yang Xu#; Alisol B 23-acetate-induced HepG2 hepatoma cell death through mTOR signalinginitiated G (1) cell cycle arrest and apoptosis: A quantitative proteomic study, Chinese Journal of Cancer Research, 2019, 31(2): 375-388
(5) Chen X, Cao X, Tu X, Alitongbieke G, Xia Z, Li X, Chen Z, Yin M, Xu D, GuoS, Li Z, Chen L, Zhang X, Xu D, Gao M, Liu J, Zeng Z, Zhou H, Su Y, Zhang XK.BI1071, a Novel Nur77 Modulator, Induces Apoptosis of Cancer Cells by Activatingthe Nur77-Bcl-2 Apoptotic Pathway. Mol Cancer Ther. 2019;18(5).
Email: Jieliu@xmu.edu.cn
