Ying-Kun Qiu,  Ph.D.

Associate Professor

Course leader of "Natural Medicinal Chemistry", the first batch of national-level first-class undergraduate courses.

Winner of “Fujian Provincial Outstanding Youth Fund”

Winner of "Fujian Provincial Higher Education New Century Excellent Talents Support Program"

Committee Member of Traditional Chinese Medicine and Natural Medicine Professional Committee of Fujian Pharmaceutical Association

Experience

September 1994 ~ July 1998: Traditional Chinese Medicine, Bachelor, Department of Traditional Chinese Medicine, Shenyang Pharmaceutical University

September 1998 ~ December 2002: Medicinal Chemistry, Ph.D., Department of Phytochemistry, Shenyang Pharmaceutical University

March 2001 ~ April 2002: Researcher, Department of Pharmacognosy, Kyoto Pharmaceutical University, Japan

January 2003 ~ March 2004: Project Leader, New Product Department, Yangtze River Pharmaceutical Group Co. Ltd.

April 2004 ~ January 2008: Lecturer, Department of Pharmaceutical Analysis and Department of Pharmacognosy, School of Pharmacy, Yantai University

April 2004 ~ October 2007: Project Director, Natural Medicine Engineering Technology Research Center of Shandong Provincial

June 2005 ~ March 2008: Postdoctoral Fellow, Liaoning University of Traditional Chinese Medicine

From February 2008 to now: Associate Professor, School of Pharmaceutical Sciences, Xiamen University

Research

ResearchDirection: Research and development of traditional Chinese medicine and marine drugs; Development and method application of multi-dimensional chromatography system; Natural products of metabolic diseases such as diabetes and cardiovascular system diseases. Presided over projects such as the National Natural Science Foundation of China Youth Project, Fujian Province Outstanding Youth Fund, the Ministry of Education's Fundamental Research Fund Project for Universities, and the Fujian Provincial Natural Science Foundation of China, etc. Undertook the census of the fourth national census of traditional Chinese medicine resources in Xiamen. As a science and technology commissioner of Fujian Province, helped Shiming Village, Changtai County, Zhangzhou City in the planting and industrial application of Chinese medicinal materials such as Changguo mulberry. As the main researcher, he participated in the research work of 863 sub-projects, the Eleventh Five-Year Major New Drug Creation Project and other research projects.Published more than 100 papers, including more than 60 SCI papers, and obtained 17 patent authorizations as a core inventor.

Selected Publications (last 5 years):

1.                Qin, J.; Chen, X.; Liu, W.; Chen, J.; Liu, W.; Xia, Y.; Li, Z.; Li, M.; Wang, S.; Yuan, Q.; Qiu, Y. *; Wu, Z. *; Fang, M. *, Discovery of 5-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)-1H-indole-2-carboxamide derivatives as novel anti-cancer agents targeting Nur77. European Journal of Medicinal Chemistry 2022, 244, 114849.

2.                Peng, A.; Liu, S.; Fang, L.; Zhu, Z.; Zhou, Y.; Yue, S.; Ma, Z.; Liu, X.; Xue, S.; Qiu, Y *.; Qi, R.*, Inonotus obliquus and its bioactive compounds alleviate non-alcoholic fatty liver disease via regulating FXR/SHP/SREBP-1c axis. European Journal of Pharmacology 2022, 921.

3.                Liu, S. Z.; Zhang, J. Y.; He, F. M.; Fu, W. H.; Tang, B. W.; Bin, Y. L.; Fang, M. J.; Wu, Z.; Qiu, Y. K. *, Anti-inflammatory sesquiterpenoids from the heartwood of Juniperus formosana Hayata. Fitoterapia 2022, 157.

4.                Liu, S. Z.; Xu, G. X.; He, F. M.; Zhang, W. B.; Wu, Z.; Li, M. Y.; Tang, X. X. *; Qiu, Y. K. *, New Sorbicillinoids with Tea Pathogenic Fungus Inhibitory Effect from Marine-Derived Fungus Hypocrea jecorina H8. Mar Drugs 2022, 20, (3).

5.                  Jia, J. X.; Kang, Q.; Liu, S. Z.; Song, Y. B.; Wong, F. S.; Qiu, Y. K. *; Li, M. Y. *, Artemether and aspterric acid induce pancreatic alpha cells to transdifferentiate into beta cells in zebrafish. Brit J Pharmacol 2022, 179, (9), 1962-1977.

6.                  Tang, X.-X.; Yan, X.; Fu, W.-H.; Yi, L.-Q.; Tang, B.-W.; Yu, L.-B.; Fang, M.-J.; Wu, Z.; Qiu, Y.-K. *, New β-Lactone with Tea Pathogenic Fungus Inhibitory Effect from Marine-Derived Fungus MCCC3A00957. J. Agric. Food Chem. 2019, 67, (10), 2877-2885.

7.                  Tang, X.-X.; Liu, S.-Z.; Yan, X.; Tang, B.-W.; Fang, M.-J.; Wang, X.-M.; Wu, Z.; Qiu, Y.-K.*, Two new cytotoxic compounds from a deep-sea Penicillum citreonigrum XT20-134. Mar. Drugs 2019, 17, (9), 509.

Tel: +86-592-2189597

Fax: +86-592-2189597

Email:  qyk@xmu.edu.cn